FREE GROUND SHIPPING ON ALL ORDERS OVER $49
TRACK YOUR ORDER
CONTACT US
FAQS

FREE SHIPPING FOR ALL ORDERS OF $49

Petstup.com
Login / Register
0 items / $0.00
Menu
Petstup.com
Login / Register
0 items / $0.00
  • Shop For Dogs
    • Dog Food
      • Dehydrated Food
      • Dry Food
      • Wet Food
      • Food Toppings
    • Crates, Pens & Gates
      • Crate Mats & Pads
      • Crates
      • Dog Houses
    • Dog Treats
      • Dental Treats
      • Training Treats
      • Jerky Treats
      • Rawhide-Free Treats
    • Dog Beds
      • Pillow Beds
      • Sofa Beds
      • Blankets
    • DOG Toys
      • Chew Toys
      • Plush Toys
      • Fetch Toys
      • Interactive Toys
    • Harnesses
      • Harnesses
      • Collars
      • Leashes
    • Healthcare
      • Dental Care
      • Ear Care
      • Eye Care
      • Milk Replacers
    • Bowls & Feeders
      • Bowls & Dishes
      • Travel Bowls
      • Storage & Accessories
    • Vitamins & Supplements
      • Hip & Joint
      • Skin & Coat
      • Eye Care
      • Multivitamins
    • Grooming
      • Grooming Tools
      • Bath & Shower Supplies
      • Shampoos & Conditioners
    • Cleaning & Potty
      • Pee Pads & Diapers
      • Stain Removers
    • Flea & Tick
      • Sprays & Wipes
      • Topical Treatments
    • Clothing & Accessories
      • Shirts
      • Accessories
      • Coats & Jackets

    Shop all >

  • Shop For Cats
    • Cat Food
      • Dehydrated Food
      • Dry Food
      • Wet Food
      • Premium Food
    • Litter & Accessories
      • Litter Boxes
      • Litter Box Accessories
      • Cleaners & Deodorizers
    • Cat Treats
      • Dental Treats
      • Catnip & Cat Grass
      • Crunchy Treats
      • Soft & Chewy Treats
    • Cat Beds
      • Covered Beds
      • Bolster Beds
      • Pillow Beds
    • Cat Toys
      • Chew Toys
      • Teasers & Wands
      • Scratchers
      • Balls & Chasers
    • Harnesses
      • Leashes & Harnesses
      • Collars
      • ID Tags & Accessories
    • Healthcare
      • Hairball Control
      • Ear Care
      • Eye Care
      • Dental Care
    • Bowls & Feeders
      • Elevated Bowls
      • Filters & Pumps
      • Storage & Accessories
    • Vitamins & Supplements
      • Urinary & Kidney
      • Skin & Coat
      • Eye Care
      • Dietary Supplements
    • Grooming
      • Grooming Tools
      • Brushes & Combs
      • Shampoos & Conditioners
    • Carriers & Travel
      • Travel Bowls & Bags
      • Car Accessories
    • Flea & Tick
      • Sprays & Wipes
      • Topical Treatments
    • Clothing & Accessories
      • Shirts & Dresses
      • Accessories
      • Jackets & Coats

    Shop all >

  • Shop By Brand
    Zuke's
    Zoo Med
    YML
    Xtreme Catnip
    XPOWER
    WHIMZEES
    Wellness
    VetIQ
    Under the Weather
    TRIXIE
    The Honest Kitchen
    Stella & Chewy’s

    View All Brands >

  • New Arrivals
  • Sales
  • Blog
  • SHOP OTHER PETS
Home Dog Flea & Tick Advantage II Flea Treatment for Large Dogs, 21-55 lbs
Advantage II Flea Treatment for Medium Dogs, 11-20 lbs $43.98 – $58.98
Back to products
Advantage II Flea Treatment for Extra Large Dogs, over 55 lbs $43.98 – $58.98
-32%Hot
Click to enlarge
Bayer

Advantage II Flea Treatment for Large Dogs, 21-55 lbs

Rated 5.00 out of 5 based on 2 customer ratings
(2 customer reviews)

$43.98 – $58.98

Add $49.00 to cart and get free shipping!
4 Doses
6 Doses
Clear

— OR —

Add to wishlist
2702 People watching this product now!
SKU: N/A Categories: Topical Treatments, Dog, Flea & Tick
Share:
  • Description
  • Additional information
  • About Bayer
  • SHIPPING & DELIVERY
Description

Description

Details

Description

Help protect your furry friend from parasitic pests and the potentially harmful diseases they can transmit with Advantage II Flea Treatment for Large Dogs. This highly-effective, veterinarian-recommended treatment is specifically formulated to kill all life stages of fleas on contact with no painful biting required. With three-way protection that kills the eggs, larvae and adults, it breaks the flea life-cycle to help prevent re-infestation of both your house and hound. The waterproof formula for dogs 7 weeks or older and weighing between 21 and 55 pounds continues working for up to four weeks, even after bathing or swimming.

Key Benefits

  • Veterinarian-recommended treatment kills all life stages of fleas on puppies and dogs 7 weeks or older and weighing 21-55 pounds.
  • Begins working within 12 hours to kill fleas on contact.
  • Kills eggs, larvae and adult fleas to break the life cycle and help prevent re-infestation.
  • Waterproof formula continues working for up to four weeks, even after bathing or swimming.
  • Convenient, monthly topical application contains imidacloprid and pyriproxyfen; available in packs of 4 or 6 treatments.

Precautions

For use only on dogs and puppies 7 weeks and older and weighing 21 – 55 lbs. DO NOT USE ON CATS. Keep out of reach of children. If your dog is on medication, consult your veterinarian before using this or any other product. Do not get this product in your dog’s eyes or allow your dog to ingest this product.

Important Information

Fleas rise to the top of your pet’s coat as they die, so consider it a triumph if you start seeing more fleas at first, after treating your pet. If you’re still seeing fleas after application, it may be because your pet has picked up new fleas from the environment, which may include other pets, surfaces and outdoor areas. It may take up to 30 days to break the entire flea life cycle. Additionally, you should also treat sources of new fleas (i.e., carpet, yard, etc.) to ensure complete flea control.

Ingredients

Active Ingredients : Imidacloprid 9.10% , Pyriproxyfen 0.46%.

Instructions

How to open:

  • Be sure tube is at bottom of pouch.
  • Using scissors, cut the pouch across the top and remove tube.

How to apply:

  • Remove one applicator tube from the package.
  • Hold applicator tube in an upright position facing away from you and your pet‘s face and eyes. Pull cap off tube.
  • Turn the cap around and place other end of cap back on tube.
  • Twist cap to break seal, then remove cap from tube.
  • The dogs should be standing for easy application. Apply the entire contents of the tube evenly on the top of the back from the shoulder to the base of the tail. At each spot, part the hair until the skin is visible. Place the tip of the tube on the skin and gently squeeze to expel a portion of the solution on the skin. Do not apply an excessive amount of solution at any one spot that could cause some of the solution to run off the side of the dog. Do not get this product in your dog‘s eyes or allow your dog to ingest this product.
  • Discard empty tube.
  • Under normal conditions the product is effective for a month. However, in case of severe flea infestation, retreatment may be necessary earlier than 4 weeks. Do not retreat more often than once every 7 days. After flea control is attained, return to a monthly retreatment schedule.

Size

Dog Weight Advantage II
3 – 10 LBS Small Dog
11 – 20 LBS Medium Dog
21 – 55 LBS Large Dog
OVER 55 LBS Extra Large Dog
Additional information

Additional information

Brand

Bayer

Count

4 Doses, 6 Doses

About Bayer
bayer-banner2

Bayer

Bayer Animal Health recognizes the special bond between pets and pet parents and develops all of its healthcare products with this bond in mind. The essentials of pet health are in the hands of pet parents, including flea and tick control. Bayer is one of the leaders in the development of animal pest control solutions. From ticks, fleas and mosquitos, Bayer products have your pets covered with trusted names like Advantage and Advantix. Certain pests can carry diseases that can be serious health risks to pets. Bayer products are backed by the belief that animals deserve the same care and treatment as humans, making them a treasured Petco partner and supplier.

Bayer Animal Health products are developed for the purpose of keeping dogs and cats flea and tick free. Although you can purchase these products for both the treatment and prevention of these pests from your vet, they are also available over the counter at Petco. The line of Advantage II and Advantage products by Bayer includes monthly topical treatments for both cats and dogs, as well as household cleaning items that help eliminate fleas and ticks in carpets and furniture. Advantage is also available in shampoos, pet sprays, and outdoor sprays that keep pests at bay and pets healthy and happy. Similarly, K9 Advantix II is a regular treatment option for dogs that repels and kills not only fleas and ticks, but also prevents mosquitos, lice, and other pests from biting and infesting your pet.

For pets who prefer the convenience of a collar for flea and tick control, Seresto by Bayer is a non-greasy, odorless collar that prevents fleas and ticks for up to 8 months. Seresto is a great option for pet-parents who prefer a long-term solution rather than a once-per-month treatment. Its sustained release technology ensures that your pet remains pest free for the full 8-months as active ingredients are released in low concentrations for optimal protection.

Shop Petstup for easy access to all Bayer Animal Health products and make your commitment to healthy, happy pets.

SHIPPING & DELIVERY

Shipping Rates

FREE Ground Shipping!On orders over $494-8 Business Days
Ground Shipping$5.954-8 Business Days
Priority Shipping$9.952-4 Business Days
Express Shipping$34.951-2 Business Day
Canada & UK Shipping$24.99TBD
International Shipping$36.50Up to 14 Business Days
Pet Food Ground ShippingStarting at $29.957-12 Business Days
Vaccine Shipping$34.95TBD

2 reviews for Advantage II Flea Treatment for Large Dogs, 21-55 lbs

  1. Rated 5 out of 5

    This product makes my life much easier – December 20, 2021

    During the time i’ve had pets as part of the family flea problems have always been the one negative part of that otherwise wonderful experience. Over the years I have explored many solutions to the flea problem with mixed results. I’ve tried the so called natural solutions and the different brands of products to keep my pets flea free and the results quite frankly have often been frustrating. Eventually I noticed good reviews for Advantage ll and tried it. Well, I can tell you that this product finally gave me what I was looking for. A safe and effective answer to my problem that is easy to use and just works! I am grateful to finally to have the answer i looked for for so long and I will be using Advantage ll for so long as I enjoy having pets. Thank you for a fine product. Sincerely JJM

  2. Rated 5 out of 5

    Great price for a product I trust. – January 17, 2022

    My dogs do not have any adverse reactions and It seems to take care of any fleas!

Add a review Cancel reply

You must be logged in to post a review.

Related products

-28%Hot
Select options
Quick view
Compare
Add to wishlist

K9 Advantix II Flea & Tick Treatment for Small Dogs, 4-10 lbs

Rated 5.00 out of 5
$28.98 – $67.98
Select options
Quick view
Compare
Add to wishlist

JW Pet Skid Stop Slow Feed Dog Bowl, Color Varies

$2.72 – $5.01
Add to cart
Quick view
Compare
Add to wishlist

Freshpet Vital Chicken Recipe Grain-Free Small Breed Fresh Dog Food, 1-lb bag, case of 6

$49.74
Select options
Quick view
Compare
Add to wishlist

Royal Canin Veterinary Diet Hydrolyzed Protein Adult HP Dry Dog Food

Rated 5.00 out of 5
$47.99 – $104.99
-28%Hot
Select options
Quick view
Compare
Add to wishlist

K9 Advantix II Flea & Tick Treatment for Large Dogs, 21-55 lbs

Rated 5.00 out of 5
$28.98 – $67.98
-32%
Select options
Quick view
Compare
Add to wishlist

Advantage II Flea Treatment for Small Dogs, 3-10 lbs

Rated 5.00 out of 5
$43.98 – $58.98
-25%Hot
Select options
Quick view
Compare
Add to wishlist

Blue Buffalo Wilderness Salmon Recipe Grain-Free Adult Dry Dog Food

Rated 5.00 out of 5
$20.98 – $62.98
-3%
Select options
Quick view
Compare
Add to wishlist

Purina Pro Plan FortiFlora Canine Probiotic Supplement for Dogs

$30.99 – $179.97
Add to cart
Quick view
Compare
Add to wishlist

Espree Natural Rainforest Dog Cologne, 4-oz

$8.75
Select options
Quick view
Compare
Add to wishlist

Stella & Chewy’s Chewy’s Chicken Dinner Patties Freeze-Dried Raw Dog Food

Rated 5.00 out of 5
$14.95 – $42.99
-11%Hot
Select options
Quick view
Compare
Add to wishlist

Hill’s Science Diet Adult Sensitive Stomach & Skin Chicken Recipe Dry Dog Food

Rated 5.00 out of 5
$17.49 – $64.99
Add to cart
Quick view
Compare
Add to wishlist

Eukanuba Chicken, Rice & Vegetables Dinner Adult Wet Dog Food, 13.2-oz, case of 12

$27.48
-21%
Select options
Quick view
Compare
Add to wishlist

Blue Buffalo Life Protection Formula Adult Lamb & Brown Rice Recipe Dry Dog Food

Rated 5.00 out of 5
$18.98 – $58.98
-59%
Select options
Quick view
Compare
Add to wishlist

KONG AirDog Squeaker Football Dog Toy

Rated 5.00 out of 5
$4.49 – $6.31
-8%
Add to cart
Quick view
Compare
Add to wishlist

Greenies Chicken Flavored Soft Chew Joint Supplement for Dogs, 80 count, 29-oz bag

$37.99 $34.99
-3%
Select options
Quick view
Compare
Add to wishlist

Freshpet Vital Balanced Nutrition Chicken & Whole Grains Fresh Dog Food

Rated 5.00 out of 5
$19.96 – $62.32

Sign Up for Emails

Receive our latest news and offers!

Connect With Us

  • Our CATEGORIES
    • Shop for Dog
    • Shop for Cat
    • Shop for Small Pet
    • Shop for Bird
    • Shop for Fish
    • Shop for Reptile
    • Shop for Horse
  • My account
    • Login / Register
    • Shopping cart
    • Track Your Order
    • My account
    • My Wishlist
    • Blog
  • Customer Service
    • About us
    • Returns
    • Help Center
    • Shipping Info
    • Contact Us
  • Help & Information
    • Refund and Returns
    • Privacy Policy
    • Terms & Conditions
    • Shipping & Delivery
    • FAQs
Petstup.com 2021 Petstup Animal Supplies. All rights reserved.
  • Shop by Dog
    • Food
    • Treats
    • Toys
    • Healthcare
    • Vitamins & Supplements
    • Cleaning & Potty
    • Crates, Pens & Gates
    • Beds
    • Leashes, Collars & Harnesses
    • Bowls & Feeders
    • Grooming
    • Flea & Tick
    • Clothing & Accessories
    • Training & Behavior
    • Technology
  • Shop by Cat
    • Food
    • Litter & Accessories
    • Treats
    • Toys
    • Healthcare
    • Vitamins & Supplements
    • Flea & Tick
    • Training & Cleaning
    • Bowls & Feeders
    • Beds
    • Trees, Condos & Scratchers
    • Carriers & Travel
    • Leashes, Collars & Harnesses
    • Crates, Pens & Gates
    • Grooming
    • Clothing & Accessories
    • Technology
  • Shop by Small Pet
    • Rabbit
    • Guinea Pig
    • Hamster
    • Ferret
    • Rat
    • Hedgehog
    • Shop All Pets
  • Shop by Bird
    • Parakeet
    • Cockatiel
    • Parrot
    • Chicken
    • Conure
    • Wild Bird
    • Shop All Birds
  • Shop by Fish
    • Food
    • Tanks & Aquariums
    • Tank Décor
    • Water Care
    • Filters & Media
    • Cleaners & Pumps
    • Heating & Lighting
    • Health & Wellness
    • Pond Shop
    • Shop Fish Deals
  • Shop by Reptile
    • Bearded Dragon
    • Turtle & Tortoise
    • Lizard
    • Snake
    • Frog
    • Hermit Crab
  • Shop by Horse
    • Concentrate Feed & Ration Balancers
    • Complete Feed
    • Forage & Hay
    • Treats & Licks
    • Joint Health & Hoof Care
    • Digestive Care & Probiotics
    • Calming
    • Performance & Recovery
    • Skin & Coat
    • Vitamins, Minerals & Overall Health
    • Pest Control
    • Dewormers
    • Hoof Care
    • First Aid
    • Grooming
    • Pharmacy
  • Blog
    • Health
    • Breeds
    • Nutrition
    • Training
    • Lifestyle
    • New Pets
  • New Arrivals
  • Shop By Brand
  • Track Your Order
  • Wishlist
  • Wishlist
  • Compare
  • Login / Register
Shopping cart
close

Sign in

close

Lost your password?

No account yet?

Create an Account

Advantage II Flea Treatment for Large Dogs, 21-55 lbs

Rated 5.00 out of 5
$43.98 – $58.98 Select options
Compare
Add to wishlist
Start typing to see products you are looking for.
Shop
Wishlist
0 items Cart
My account